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patents

Spectros has 80 US and international patents and counting...

Spectros and its affiliates have over 80 patents issued, licensed, or filed worldwide for molecular sensing, detection, and imaging, forming one of the largest biophotonics intellectual property collections.

Our innovative approach centers on key patented core technology families, covering optical spectroscopy, fluorimetry, and imaging for use in blood analysis, contrast-targeted cancer surgery, lab-on-chip systems, and benchtop life-sciences equipment. Based on these technology families, Spectros develops, markets, and licenses a number of medical and industrial optical products and processes, including OEM components and devices and medical devices both under study and on the market.

Because of this, Spectros aggressively defends its technologies and products against infringement, including:

T-Stat Ischemia Monitoring Patents
FireFly® Surgical Guidance Patents
Cancer Detection/Imaging Patents
Broadband Illumination Patents
Multispectral Pulse Oximetry Patents

A selected set of these patents are listed in the table below.

T-Stat® Ischemia Detection
Patent Number	Year	Size	Description
under review	pending	- - -	Broadband Probe for Noninvasive Deep Tissue Ischemia and Cancer Detection and Monitoring
US 2009/0187076	pending	- - -	Integrated White LED illuminator and Color Sensor
US 2009/0048502	pending	- - -	Broadband pulse oximeter and/or tissue oximeter for CarboxyHemoglobin, MetHemoglobin, Bilirubin, and others
US 2008/0304793	pending	1 Mb	Optical and Electrical Hybrid Connector
US 2008/0287758	pending	1 Mb	Illuminator probe with memory device and method
US 2008/0226137	pending	1 Mb	Living vs. Dead Tissue or Non-Tissue Discrimination
US 2008/0188727	pending	1 Mb	Broadband solid-state spectroscopy illuminator and method
US 2008/0009689	pending	1 Mb	Somatic Ischemia Monitoring
US 2007/0015981	pending	1 Mb	Local Ischemia Detection and Monitoring
US 7,427,165	2008	1 Mb	Connector and Probe Design Including Optical Fiber for Oximetry and Other Medical Uses
US 7,062,306	2006	2 Mb	Broadband Oximeter
US 6,711,426	2004	2 Mb	Broadband Illuminator Using White LED
US 6,594,518	2003	2 Mb	Optical probe design
US 5,752,519 *	1998	2 Mb	Optical Characterization of Tissue
US 5,746,210 *	1998	2 Mb	Optical Characterization of Tissue
US 5,337,745 *	1994	1 Mb	Measuring Blood Components with Multi-wavelength Oximetry

FireFly® Surgical Guidance Patents
Patent Number	Year	Size	Description
US 2008/0226137	pending	1 Mb	Living vs. Dead Tissue Discrimination
US 2008/0188727	pending	1 Mb	Broadband solid-state spectroscopy illuminator and method
US 2008/0009689	pending	1 Mb	Somatic Ischemia Monitoring
US 2007/0015981	pending	1 Mb	Ischemia Detection and Monitoring
US 6,869,430* (patent and patent family shared with Rita Medical)	2005	- - -	Tissue thermal ablation and treatment apparatus and method for cancer and other lesions
US 6,711,426	2004	2 Mb	Broadband Illuminator Using White LED
US 6,594,518	2003	2 Mb	Optical probe design
US 6,246,901 (issued Europe as EP1196763 and issuing in Japan)	2001	2 Mb	Use of optical contrast agents to guide cancer surgery, including breast and prostate cancer
US 6,167,297 (issued Europe as EP1196763 and issuing in Japan)	2000	2 Mb	Use of optical contrast agents to target interventions
US 5,987,346 (issued Europe as EP1006875 and issuing in Japan)	1999	3 Mb	Classifying Tissue by Type (e.g., liver, nerve, blood vessel), , State (e.g., ablated, frozen, thawed), or Liveness (e.g., living vs. dead, especially during a procedure
US 5,807,261 *	1999	2 Mb	Noninvasive Tissue Characterization
US 5,785,658 *	1998	2 Mb	In Vivo Tissue Analysis
US 5,772,597 *	1998	2 Mb	Surgical Tool End Effector
US 5,769,791 *	1998	2 Mb	Tissue Interrogating Methods
US 5,762,609 *	1998	2 Mb	Surgical Tissue Interventions
US 5,752,519 *	1998	2 Mb	Classification of Tissue
US 5,746,210 *	1998	2 Mb	Classification of Tissue

Cancer Screening and Imaging Patents
under review	pending	- - -	Contrast agents for in vivo Cancer Detection
under review	pending	- - -	Probe design for Cancer Detection
US 2008/0241065	pending	1 Mb	Nanobots for Cancer Detection (one of the first U.S. patent applications to claim nanobots in cancer treatment and detection).
US 2008/0214940	pending	1 Mb	Real-Time, Room Light Intraoperative Dye/Fluorescence Imaging
US 2007/0093708	pending	1 Mb	Breast Cancer Detection
US 6,748,259	2004	3 Mb	Optical Imaging of Induced Signals in Room Light
US 6,246,901 (issued Europe as EP1196763 and in Japan)	2001	2 Mb	Use of optical contrast agents to guide cancer surgery, including breast and prostate cancer
US 6,167,297 (issued Europe as EP1196763 and in Japan)	2000	2 Mb	Use of optical contrast agents to target interventions

Broadband Illuminator for Spectroscopy and Color Sensing Patents
Patent Number	Year	Size	Description
under review	pending	- - -	Multispectral Oximetry probe
under review	pending	- - -	Color Sensor with White LED
US 2009/0048502	pending	1 Mb	Broadband pulse oximeter and/or tissue oximeter for CarboxyHemoglobin, MetHemoglobin, Bilirubin, and others
US 2008/0304793	pending	1 Mb	Optical and Electrical Hybrid Connector
US 2008/0287758	pending	1 Mb	Illuminator probe with memory device and method
US 2008/0188727	2008	2 Mb	Solid-State Illuminator for Spectroscopy, Color Sensing, and Lab-in-Chip
US 7,427,165	2008	1 Mb	Connector and Probe Design Including Optical Fiber for Oximetry and Other Medical Uses
US 7,062,306	2006	2 Mb	Broadband Spectroscopy Pulse Oximeter Measuring Oxygenation, met-Hemoglobin, Carboxy-hemoglobin, Bilirubin
US 6,711,426	2004	2 Mb	Broadband Spectroscopy Illuminator Using White LED for Spectroscopy, Color Sensing, Lab-on-Chip
US 5,337,745 *	1994	1 Mb	Measuring Blood Components with Multi-wavelength Oximetry, including abnormal hemoglobin (e.g., MetHb, COHb, HbA1c)

Multispectral Pulse Oximetry Patents
Patent Number	Year	Size	Description
under review	pending	- - -	Probe design for Pulse Oximetry use
under review	pending	- - -	Probe Illuminator design for Pulse Oximetry Use
US 2009/0048502	pending	1 Mb	Broadband Spectroscopy Pulse Oximeter Measuring Oxygenation, met-Hemoglobin, Carboxy-hemoglobin, Bilirubin
US 2008/0287758	pending	1 Mb	Illuminator probe with memory device and method
US 2008/0188727	pending	2 Mb	Solid-State Illuminator for Spectroscopy, Color Sensing, and Lab-in-Chip
US 7,427,165	2008	1 Mb	Connector and Probe Design Including Optical Fiber for Oximetry and Other Medical Uses
US 7,062,306	2006	2 Mb	Broadband Spectroscopy Oximeter Measuring Oxygenation, met-Hemoglobin, carboxy-hemoglobin
US 5,337,745 *	1994	1 Mb	Measuring Blood Components with Multi-wavelength Oximetry, including abnormal hemoglobin (e.g., MetHb, COHb, HbA1c)

* = Acquired or in-licensed

patents

Spectros has 80 US and international patents and counting...

T-Stat® Ischemia Detection

FireFly® Surgical Guidance Patents

Cancer Screening and Imaging Patents

Broadband Illuminator for Spectroscopy and Color Sensing Patents

Multispectral Pulse Oximetry Patents