Spectros

Real-Time Tissue Perfusion Monitors

Plastic Surgery

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White Light Spectroscopy for Free Flap Monitoring

The Spectros T-Stat monitoring device, which utilizes white light spectroscopy, is compared with traditional flap monitoring techniques. T-Stat measures hemoglobin saturation at the capillary level rendering a valuable end-organ measurement of per- fusion during free tissue flap procedures.

Paige M. Fox, M.D., Ph.D.,1 Kamakshi Zeidler, M.D.,1 Joseph Carey, M.D.,2 and Gordon K. Lee, M.D.,1* 

 

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The Use of Visible Light Spectroscopy to Measure Tissue Oxygenation in Free Flap Reconstruction

The loss of a free flap is a feared complication for both the surgeon and the
patient. Early recognition of vascular compromise has been shown to provide the best
chance for flap salvage.

Agustin Cornejo, M.D.,1,2 Thomas Rodriguez, M.S.,1,2 Megan Steigelman, M.D.,2
Stacy Stephenson, M.D.,1,2 David Sahar, M.D.,1,2 Stephen M. Cohn, M.D.,2
Joel E. Michalek, Ph.D.,3 and Howard T. Wang, M.D.1,2

 

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Free Flap Monitoring with T-Stat

T-Stat measure both St02% and Hemoglobin to determine arterial vs venous occlusions.

 

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Change In Skin Saturation Over Time with T-Stat by Spectros

Change In Skin Saturation Over Time with Arterial Occlusion Measured with T-Stat

 

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Venous Occlusion Measured with T-Stat

The use of the T-Stat gives earlier warning signs when time is most critical in the success of saving a compromised free flap.

 

 

G.I. Endoscopy

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Why measure in the G.I. tract

When measurements are taken throughout the body the results are not always predic- tive, nor reliable. The skin is very sensitive to the surrounding environment and is not a reliable way to monitor tissue saturation. Monitoring in the brain gives results that are not reproducible and do not provide an early warning. However, if measurements are taken in the GI tract, there is the benefit of early diagnosis.

 

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Contribution of Capillary, Venous & Arterial Blood in O2 Sat by T-Stat

The contribution of capillary, venous and arterial blood in the oxygen saturation reported by the T-Stat VLS Tissue Oximeter

 

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Friedland - Detection of Enteric Ischemia Using T-Stat

S Friedland, R Soetikno, V Gowra and G Singh, Dept. of Gastroenterology, Stanford University School of Medicine, Palo Alto, CA 94304

 

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Karliczek - Reflectance Spectrometry As Intraoperative Assesment of Perfusion in Rectal

Reflectance Spectrometry As Intraoperative Assesment Of Perfusion In Colorectal Anastomosis : A Feasibility Study

 

A. Karliczek, D.A. Benaron, P.C. Baas, A. van der Stoel, T. Wiggers, G.M. van Dam 

1. Martini Hospital Groningen, Groningen, The Netherlands 

2. Spectros Corporation, Portola Valley, USA 

3. University Medical Center Groningen, Groningen, The Netherlands D

 

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Mensink - Diagnosis of Chronic Mesenteric Ischemia Using T-Stat

J Surg Res. 2006 Nov;136(1):19-24.

 

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van Noord - Endoscopic VLS for Diagnosis of GI Ischemia.pdf

Endoscopic visible light spectroscopy: a new minimally invasive technique for the diagnosis of chronic gastrointestinal ischemia.

Désirée van Noord MD1, Peter M.T. Pattynama MD PhD2, Hence J.M. Verhagen MD PhD3, Bettina E. Hansen PhD4, Ernst J. Kuipers MD PhD1, Peter B.F. Mensink MD PhD1

 

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Wang - Continuous GI Mucosal Oximetry During EVAR

Continuous gastrointestinal mucosal oximetry during endovascular procedures carrying risk of ischemia

SL Wang, DY Sze, MD Dake, S Friedland, DA Benaron, and MK Razavi Department of Interventional Radiology, Stanford University School of Medicine, Palo Alto, CA 94304 USA

 

Neonatal ICU

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Critical Care PAC vs T-Stat

Now there is a new noninvasive way to continuously monitor your patient with the T-Stat VLS (Visible Light Spectroscopy) Tissue Oximeter.

 

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Correlation of Visible Light Spectroscopy with Mixed Venous Oxygen Saturation in Post-operative Congenital Heart Patients

Tracey VanVliet RN CCRP, Samuel Hanke MD, Catherine, D. Krawczeski MD
Loma Linda University Medical Center, Presented at ASA 2010

 

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Esophageal and Buccal Mucosal Oxygen Saturation in Patients Undergoing Cardio-Puklmonary Bypass - Loma Linda University

Mucosal saturation determined by visible light spectroscopy (StO2) may measure tissue perfusion, which may be useful during anesthesia.

 

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Regional StO2 in an Animal Model - Loma Linda University

Regional Tissue Oxygen Saturation in an Animal Model of Global and Regional Oxygen Delivery Insults

 

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Technology Comparison

Our medical devices build upon state-of-the-art optical molecular technologies to speed diagnosis, reduce complications, and lower costs.

 

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Tissue-Pulse Oximeter Differences Related to Local Tissue Perfusion

This neonatal case shows how pulse and tissue oximetry co-vary as perfusion changes.

 

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Why measure in the G.I. tract

When measurements are taken throughout the body the results are not always predic- tive, nor reliable. The skin is very sensitive to the surrounding environment and is not a reliable way to monitor tissue saturation. Monitoring in the brain gives results that are not reproducible and do not provide an early warning. However, if measurements are taken in the GI tract, there is the benefit of early diagnosis.

 

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Contribution of Capillary, Venous & Arterial Blood in O2 Sat by T-Stat

The T-Stat® Microvascular Tissue Oximeter provides a continuous, noninvasive measurement of the microvascular hemoglobin oxygen saturation, sensitive to reduced-flow or no-flow ischemia, as demonstrated in peer-reviewed human clinical studies. 

 

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Ramamoorthy - Prospective Detection of Ischemia During Hypothermic Circulatory Arrest Using VLS

Visible light spectroscopy (VLS) is a real-time, quantitative monitor of tissue ischemia. We used VLS to detect tissue oxygenation in CPB.

Abstract A - 1513

 

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T-Stat During Induced Hemorrhagic Shock

This case data shows somatic (esophageal) and cranial (internal carotid distribution) saturation monitored during in a neonatal piglet model during acute hemorrhage. 

2004 Jun;100(6):1469-75.

 

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T-Stat on Newborn Full-Term Infant With Cardiac Failure

This case data shows esophageal saturation via T-Stat® Sto2 on an infant with cardiac failure due to ventricular aneurysm, admitted from the Delivery Room, dusky and floppy.

Anesthesiology. 2004;100(6):1469-1475.

 

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T-Stat StO2 vs. Somanetics INVOS during Brief Cardiac Arrest

This case report compares T-Stat® Sto2 as measured in the oral cavity (buccal mucosa), and INVOS® rSo2 as measured on the forehead, during cardiac repair with cardiac standstill.

Anesthesiology. 2004 Jun;100(6):1469-75.

 

Cardiac Surgery, Bariatric Surgery, Other Surgery

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Correlation of Visible Light Spectroscopy with Mixed Venous Oxygen Saturation in Post-operative Congenital Heart Patients

Tracey VanVliet RN CCRP, Samuel Hanke MD, Catherine, D. Krawczeski MD
Loma Linda University Medical Center, Presented at ASA 2010

PDF dokument

Esophageal and Buccal Mucosal Oxygen Saturation in Patients Undergoing Cardio-Puklmonary Bypass - Loma Linda University

Mucosal saturation determined by visible light spectroscopy (StO2) may measure tissue perfusion, which may be useful during anesthesia.

 

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Comparison of VLS Tissue StO2 to PAC Venous SvO2

Visual light spectroscopy reflects flow-related changes in brain oxygenation during regional low-flow perfusion and deep hypothermic circulatory arrest

1308 The Journal of Thoracic and Cardiovascular Surgery December 2006

 

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Detection of regional myocardial tissue ischemia using visible light spectroscopy in a pig model

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T-Stat StO2 vs. Somanetics INVOS during Brief Cardiac Arrest

2004 Jun;100(6):1469-75.

 

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Van der Starre - Optical Tissue Oximetry During CPB

First Clinical Experiences with Non-Pulsatile Optical Diffusion Tissue Oximetry during Cardiopulmonary 

October 11 – 15, 2003 Anesthesiology 2003; 99: A558

 

Anesthesiology

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Lee Study - Use of T-Stat to Predict Colonic Ischemia

Use of T-Stat to predict colonic ischemia during and after endovascular aneurysm repair: A case report

© 2008 by The Society for Vascular Surgery. doi:10.1016/j.jvs.2007.09.037

 

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Heninger Study - Esophageal Saturation During ACP

Esophageal saturation during antegrade cerebral perfusion: a preliminary report using visible light spectroscopy

2006 Blackwell Publishing Ltd, Pediatric Anesthesia, 16, 1133–1137

 

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Brock-Utne Abstract - Intraoperative Colon Mucosal Oxygen Saturation Can Predict Colon Ischemia

Intraoperative Colon Mucosal Oxygen Saturation Can Predict and Possibly Prevent Colon Ischemia During Aortic Aneurysm Repair

(Rev 05.06.13) Accepted For Presentation at ASA 2005

 

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Van der Starre - Optical Tissue Oximetry During CPB

First Clinical Experiences with Non-Pulsatile Optical Diffusion Tissue Oximetry during Cardiopulmonary 

October 11 – 15, 2003 Anesthesiology 2003; 99: A558

 

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Amir Study - VLS Reflects Flow-Related Changes

Visual light spectroscopy reflects flow-related changes in brain oxygenation during regional low-flow perfusion and deep hypothermic circulatory arrest

The Journal of Thoracic and Cardiovascular Surgery. Volume 132, Number 6 1307

 

Vascular Surgery

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Reimer - VLS Correlates with Controlled Abdominal Aortic Flow During Low Flow

Visible Light Spectroscopy Correlates with Controlled Abdominal Aortic Flow During Regional Low Flow Perfusion 

RK Reimer, C Ramamoorthy, G Amir, FL Hanley, VM Reddy Departments of Anesthesia and Cardiovascular Medicine, Stanford University School of Medicine, Palo Alto, CA 94304 USA

 

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Brock-Utne - Intraoperative Colon Mucosal Oxygen Sat During AAA

Intraoperative Colon Mucosal Oxygen Saturation Can Predict and Possibly Prevent Colon Ischemia During Aortic Aneurysm Repair

 

(Rev 05.06.13) Accepted For Presentation at ASA 2005

 

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Friedland - Detection of Enteric Ischemia Using T-Stat

S Friedland, R Soetikno, V Gowra and G Singh, Dept. of Gastroenterology, Stanford University School of Medicine, Palo Alto, CA 94304

 

PDF dokument

Contribution of Capillary, Venous & Arterial Blood in O2 Sat by T-Stat

The T-Stat® Microvascular Tissue Oximeter provides a continuous, noninvasive measurement of the microvascular hemoglobin oxygen saturation, sensitive to reduced-flow or no-flow ischemia, as demonstrated in peer-reviewed human clinical studies. 

 

PDF dokument

Mensink - Diagnosis of Chronic Mesenteric Ischemia Using T-Stat

J Surg Res. 2006 Nov;136(1):19-24.

 

Cancer Research

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Friedland - GI Tumor Saturation Survey

To explore sensitivity of Visible Light  Spectroscopy (VLS) to detection of local  

gastrointestinal tumors.

Shai Friedland, Department of Gastroenterolgy, Stanford University School of Medicine,  Palo Alto, CA

 

Validation

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Comparison of VLS Tissue StO2 to PAC Venous SvO2

Anesthesiology. 2004 Jun;100(6):14697

 

PDF dokument

Contribution of Capillary, Venous & Arterial Blood in O2 Sat by T-Stat

The T-Stat® Microvascular Tissue Oximeter provides a continuous, noninvasive measurement of the microvascular hemoglobin oxygen saturation, sensitive to reduced-flow or no-flow ischemia, as demonstrated in peer-reviewed human clinical studies.