Early physical and laboratory signs of systemic ischemia are unreliable. In patients with the required vascular access, venous saturation has been the standard to turn to for global ischemia. Why? Because noninvasive measures such as blood pressure and arterial saturation aren’t predictive of outcome, while invasive measures such as lactate are late signs, and cannot be used for real-time management.

You said: “…if only we could monitor Svo₂ in all patients, quickly”

Intensivists already demand venous saturation (Svo₂) in their sickest patients… yet Svo₂ requires invasive sampling, and thus may not be available when you need it, nor as often as you want it.

T-Stat^® has been proven in multiple trials to be sensitive to ischemia, and is the first device allowed to be labeled "sensitive to ischemia is correlated to measures of venous saturation (r²=0.94). In the study graph shown below, patients undergoing cardiac surgery on cardiopulmonary bypass were studied using noninvasive T-Stat^® sensors. Despite cardiac arrest during surgery, T-Stat^® continued to monitor tissue saturation (Sto₂) in all patients. The relationship between Svo₂ and Sto₂ was linear, as shown: